Can differences in linear energy transfer and thus relative biological effectiveness compromise the dosimetric advantage of intensity-modulated proton therapy as compared to passively scattered proton therapy?

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Intensity modulated proton therapy.

Intensity modulated proton therapy (IMPT) implies the electromagnetic spatial control of well-circumscribed "pencil beams" of protons of variable energy and intensity. Proton pencil beams take advantage of the charged-particle Bragg peak-the characteristic peak of dose at the end of range-combined with the modulation of pencil beam variables to create target-local modulations in dose that achie...

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ژورنال

عنوان ژورنال: Acta Oncologica

سال: 2018

ISSN: 0284-186X,1651-226X

DOI: 10.1080/0284186x.2018.1468090